Click to buy
Hspa1b Polyclonal Antibody

Other name

Heat shock 70 kDa protein 1B,Hspa1b,Hcp70.1,Hsp70-1,Hsp70a1,Hspa1,Heat shock 70 kDa protein 1,HSP70.1

Immunogen

Recombinant mouse Heat shock 70 kDa protein 1B protein (2-642AA)

Verified reactivity

Mouse, Human

Verified applications

ELISA,WB. Recommended dilution:WB:1:500-2000

Raised in

Rabbit

Clonality

Polyclonal

Protein number

P17879

Gene number

Please refer to GenBank

NCBI number

Please refer to NCBI

Purity

Caprylic Acid Ammonium Sulfate Precipitation Purified

Storage recommendation

Aliquot and store at -20°C. Minimize freezing and thawing.

Use before

1 year

Shipping requirements

Blue ice

Estimated production time

3-7 business days

Supplementary information

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Essential for STUB1-mediated ubiquitination and degradation of FOXP3 in regulatory T-cells (Treg) during inflammation.

Notes

For research use only. Not for diagnostic procedures.

Properties

If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Group

Polyclonals and antibodies

About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

French translation

anticorps