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Recombinant Human Heat Shock Protein β-2//HSPB2/MKBP Protein(C-6His)

Synonym

Heat shock protein beta-2;HspB2;DMPK-binding protein;MKBP;

Activity

NA

Sequence

Met1-Pro182

Fusion tag

C-6His

Accession

Q16082

Expressed Host

E.coli

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Purity

＞95% as determined by reducing SDS-PAGE.

Endotoxin

＜1.0 EU per µg as determined by LAL test.

Stability and Storage

Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months

Mol Mass

21.3 kDa

AP Mol Mass

22 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution of 20mM HEPES,0.1MKCl,pH7.5.

Background

Heat shock protein beta-2(HSPB2) is a protein that in humans is encoded by the HSPB2 gene. HSPB2 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. It is expressed preferentially in the heart and skeletal muscle. HSPB2 has been shown to interact with TRAF6, HSPB8, Myotonic dystrophy protein kinase and CRYAB. HSPB2 regulates Myotonic Dystrophy Protein Kinase, which plays an important role in maintenance of muscle structure and function.

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Source

Recombinants or rec. proteins

Group

recombinants