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HSP60 (Heat Shock Protein 60)

Also known as

HSP60

Other names

60 kDa heat shock protein, mitochondrial; 60 kDa heat shock protein, mitochondrial; 60 kDa heat shock protein, mitochondrial; chaperonin 60; 60 kDa chaperonin; heat shock protein 65; P60 lymphocyte protein; mitochondrial matrix protein P1; short heat shock protein 60 Hsp60s1; heat shock 60kDa protein 1 (chaperonin); 60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; HSP-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein

Category

Antibodies

Subcategory

Mnoclonal antibodies

Gene name

HSPD1

Gene name synonims

N/A

Other gene names

HSPD1; HSPD1; HLD4; CPN60; GROEL; HSP60; HSP65; SPG13; HSP-60; HuCHA60; HSP60; CPN60; HSP-60; Hsp60

Clonality

Monoclonal

Immunoglobulin isotype

IgG1, kappa

Clone

GROEL730

Host organism

Mouse (Mus musculus)

Species reactivity

Human (Homo sapiens) specific. Does not react with Mouse (Mus musculus) and Rat (Rattus norvegicus).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Specificity and cross-reactivity

Recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog. Clone GROEL730 reacts only with human and is useful in distinguishing human hsp60 from other mammalian and bacterial hsp60.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Purification method

N/A

Form/Appearance

N/A

Concentration

N/A

Storage and shipping

Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.

Tested applications:

ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)